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Table 2 Laboratory parameters of the study groups (control, inactive and active ulcerative colitis)

From: Neutrophil/lymphocyte ratio and lymphocyte/monocyte ratio in ulcerative colitis as non-invasive biomarkers of disease activity and severity

  Control Inactive Active Test value p-value Post hoc analysis
No. = 40 No. = 40 No. = 40 P1 P2 P3
Hb (g/dL)
 Mean ± SD 14.09 ± 1.01 12.79 ± 1.19 12.44 ± 1.71 17.299a 0.000 0.000 0.000 0.232
 Range 12.7–16.2 10.1–15 8.6–14.1
Platelet
 Mean ± SD 314.90 ± 68.50 303.10 ± 68.30 304.55 ± 77.42 0.332a 0.718 0.456 0.513 0.927
 Range 187–413 194–413 178–411
ESR (mm/h)
 Median (IQR) 10 (6–12) 18.5 (16.5–33) 28.5 (19–46) 63.411b 0.000 0.000 0.000 0.037
 Range 2–19 10–70 12–80
CRP (mg/dL)
 Median (IQR) 0 (0–1) 2 (1–4.5) 20.5 (16–32.5) 90.859b 0.000 0.000 0.000 0.000
 Range 0–6 0–11 6–65
WBC
 Mean ± SD 5.94 ± 1.41 6.49 ± 1.41 7.54 ± 2.06 9.820a 0.000 0.140 0.000 0.005
 Range 3.9–8.59 4.55–9.49 4.21–10.29
Absolute neutrophil
 Mean ± SD 3.26 ± 0.87 3.62 ± 0.92 4.84 ± 1.46 22.566a 0.000 0.147 0.000 0.000
 Range 2.01–5.19 2.4–5.72 2.6–7
Absolute lymphocytic
 Mean ± SD 2.27 ± 0.56 2.24 ± 0.53 1.87 ± 0.59 6.491a 0.002 0.751 0.001 0.004
 Range 1.5–3 1.5–3 1–3
Absolute monocytic
 Mean ± SD 0.40 ± 0.11 0.63 ± 0.07 0.82 ± 0.15 145.993a 0.000 0.000 0.000 0.000
 Range 0.25–0.62 0.5–0.77 0.5–1
NLR
 Mean ± SD 1.44 ± 0.19 1.64 ± 0.25 2.63 ± 0.43 179.622a 0.000 0.004 0.000 0.000
 Range 1.2–1.83 1.28–2.12 1.81–3.21
LMR
 Mean ± SD 3.64 ± 0.49 3.58 ± 0.76 2.25 ± 0.51 69.838a 0.000 0.625 0.000 0.000
 Range 2.6–4.82 2.27–4.98 1.35–.03
  1. P1: control vs inactive; P2: control vs active; P3: active vs inactive
  2. ESR erythrocyte sedimentation rate, CRP C-reactive protein, WBC Wight blood cells; NLR neutrophil lymphocyte ratio, LMR lymphocyte monocyte ratio
  3. aOne Way ANOVA followed by post hoc using LSD
  4. bKruskall–Wallis test followed by post hoc using Mann–Whitney
  5. cIndependent t-test